SELANK
Selank - Regulatory Neuropeptide (Tuftsin Analog)
Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg), extended with a Gly-Pro C-terminal sequence to enhance CNS bioavailability and metabolic stability. Developed alongside Semax at the Institute of Molecular Genetics, Selank has become an important research tool for studying the intersection of immune function and neurological activity.
Mechanism of Action
Selank modulates GABAergic neurotransmission by influencing the expression of GABA-A receptor subunit genes, particularly the α3 and δ subunits. It also affects the metabolism of serotonin and its metabolite 5-HIAA, and modulates enkephalin and catecholamine levels in specific brain regions. On the immunological side, Selank influences IL-6 expression and modulates the balance of Th1/Th2 cytokine profiles, providing a dual neuroimmune research application.
Research Applications
- GABAergic modulation and anxiolytic mechanism studies
- Neuroimmune interaction research
- Serotonergic signaling studies
- Neuropeptide signaling under stress-model conditions
- Cytokine profile modulation and immune function
| Product Name | SELANK |
|---|---|
| Quantity | 10mg per vial |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | Refrigerate after reconstitution. Store lyophilized at -20°C. |
| Testing | USA lab tested. COA available on request. |
| Receptor Targets | |
| Mechanism | |
| SKU | MBR-SELANK |
| Intended Use | Research purposes only. Not for human use. |
Technical Specifications
| Product Name | — |
| Dosage / SKU | — |
| Form | Lyophilized Powder |
| Purity | ≥99% (HPLC verified) |
| Storage | -20°C long-term; 4°C short-term |
| Reconstitution | Bacteriostatic Water or Sterile Water |
| Shelf Life | 24 months from manufacture date |
| Origin | US-Based, Third-Party Verified |