IPAMORELIN
Ipamorelin - Selective Growth Hormone Secretagogue
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) that selectively stimulates growth hormone release through the ghrelin/GHS receptor (GHSR). What distinguishes Ipamorelin from other GH secretagogues is its remarkable selectivity - it promotes GH release without significantly affecting cortisol, prolactin, or ACTH levels, making it one of the cleanest research tools for isolated GH pathway studies.
Mechanism of Action
Ipamorelin binds to the growth hormone secretagogue receptor (GHSR) on pituitary somatotroph cells, triggering a calcium-dependent signaling cascade that promotes GH vesicle release. Unlike GHRP-6 and GHRP-2, Ipamorelin does not significantly stimulate appetite through ghrelin-mimetic effects and shows minimal interaction with ACTH or cortisol secretion pathways. This selectivity allows researchers to study GH-specific effects without confounding hormonal variables.
Research Applications
- Selective GH secretion and pituitary function studies
- GHS receptor (GHSR) signaling research
- Growth-hormone axis signaling investigations
- Bone mineral density and osteoblast activity studies
- Synergistic studies with GHRH analogs (e.g., CJC-1295)
- Growth-hormone axis signaling research
| Product Name | IPAMORELIN |
|---|---|
| Quantity | 10mg per vial |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | Refrigerate after reconstitution. Store lyophilized at -20°C. |
| Testing | USA lab tested. COA available on request. |
| Receptor Targets | |
| Mechanism | |
| SKU | MBR-IPAMORELIN |
| Intended Use | Research purposes only. Not for human use. |
Technical Specifications
| Product Name | — |
| Dosage / SKU | — |
| Form | Lyophilized Powder |
| Purity | ≥99% (HPLC verified) |
| Storage | -20°C long-term; 4°C short-term |
| Reconstitution | Bacteriostatic Water or Sterile Water |
| Shelf Life | 24 months from manufacture date |
| Origin | US-Based, Third-Party Verified |