MELANOTAN 2
MT-2 - Cyclic Melanocortin Receptor Agonist
MT-2 (Melanotan II) is a synthetic cyclic lactam analog of alpha-melanocyte stimulating hormone (α-MSH). Through structural modifications including cyclization and amino acid substitutions, MT-2 achieves enhanced receptor binding affinity, improved metabolic stability, and broader melanocortin receptor subtype activation compared to the native linear hormone.
Mechanism of Action
MT-2 acts as a non-selective agonist across multiple melanocortin receptor subtypes (MC1R through MC5R). MC1R activation in melanocytes stimulates eumelanin synthesis through the cAMP/PKA/MITF signaling cascade. MC3R and MC4R activation in the hypothalamus modulates melanocortin receptor pathways. The cyclic structure provides superior resistance to enzymatic degradation compared to linear melanocortin peptides.
Research Applications
- Melanogenesis and pigmentation pathway studies
- Melanocortin receptor subtype profiling (MC1R-MC5R)
- Melanocortin receptor signaling research
- UV-independent melanocyte activation research
- Comparative studies with linear melanocortin analogs
| Product Name | MELANOTAN 2 |
|---|---|
| Quantity | 10mg per vial |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | Refrigerate after reconstitution. Store lyophilized at -20°C. |
| Testing | USA lab tested. COA available on request. |
| Receptor Targets | |
| Mechanism | |
| SKU | MBR-MELANOTAN2 |
| Intended Use | Research purposes only. Not for human use. |
Technical Specifications
| Product Name | — |
| Dosage / SKU | — |
| Form | Lyophilized Powder |
| Purity | ≥99% (HPLC verified) |
| Storage | -20°C long-term; 4°C short-term |
| Reconstitution | Bacteriostatic Water or Sterile Water |
| Shelf Life | 24 months from manufacture date |
| Origin | US-Based, Third-Party Verified |